Nutritional anti-inflammatories in the treatment and prevention of type 2 diabetes mellitus and the metabolic syndrome

Diabetes Res Clin Pract. 2017 May:127:238-253. doi: 10.1016/j.diabres.2017.02.019. Epub 2017 Feb 20.

Abstract

Aims: Obesity-fuelled metabolic syndrome and diabetes is now a global epidemic. There is increasing evidence that these and other chronic conditions have common inflammatory antecedents. There is an interest in nutritionally based anti-inflammatory treatments for type 2 diabetes and metabolic syndrome. The aim of this review is to examine the evidence from a 5-year period; 2011-2016, for nutritionally based anti-inflammatory treatments for the Metabolic Syndrome and Type 2 Diabetes Mellitus.

Methods: A literature search produced a total number of 1377 records, of which 26 papers were evaluated.

Results: Literature was analysed and tabulated according to date, outcome measures and results.

Conclusion: The evidence is strong for use of polyphenolic compounds, fish oils and vitamins in reducing inflammation biomarkers, however the impact on metabolic control is less evident.

Keywords: Anti-inflammatories; Diabetes mellitus; Metabolic syndrome; Nutrition.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use*
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Humans
  • Inflammation / drug therapy*
  • Metabolic Syndrome / drug therapy*
  • Metabolic Syndrome / prevention & control*

Substances

  • Anti-Inflammatory Agents