Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens

J Allergy Clin Immunol Pract. 2017 Sep-Oct;5(5):1234-1240. doi: 10.1016/j.jaip.2017.03.001. Epub 2017 Apr 7.

Abstract

Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. This review covers preoperative, operative, and postoperative exposures that may result in contact dermatitis. Testing with standard patch panels such as T.R.U.E. Test and the North American Contact Dermatitis Group 65 allergen series does not evaluate for all relevant contactants. A thorough understanding of potential exposures is vital to effectively evaluate a patient with surgery-related contact dermatitis. A systematic approach is needed to ensure that standard patch panels and supplementary patches adequately address each encountered contactant.

Keywords: Adhesive allergy; Anesthetic; Antiseptic; Contact dermatitis; Cyanoacrylate; Surgery-related contact dermatitis.

Publication types

  • Review

MeSH terms

  • Allergens / adverse effects
  • Allergens / immunology*
  • Animals
  • Dermatitis, Allergic Contact / etiology
  • Dermatitis, Allergic Contact / immunology*
  • Environmental Exposure / adverse effects
  • Humans
  • Irritants / adverse effects
  • Irritants / immunology*
  • Patch Tests
  • Postoperative Complications / immunology*
  • Surgical Procedures, Operative*

Substances

  • Allergens
  • Irritants