How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old

C Prados; M Lerín; J J Cabanillas; L Gómez-Carrera; R Álvarez-Sala; cystic fibrosis group of Neumomadrid

doi:10.1016/j.rmcr.2017.03.015

How are the ancient cystic fibrosis patients? Cystic fibrosis diagnosed over 60 years-old

Respir Med Case Rep. 2017 Mar 24:21:49-51. doi: 10.1016/j.rmcr.2017.03.015. eCollection 2017.

Authors

C Prados¹, M Lerín¹, J J Cabanillas¹, L Gómez-Carrera¹, R Álvarez-Sala¹; cystic fibrosis group of Neumomadrid

Collaborators

cystic fibrosis group of Neumomadrid:
M T Martinez, L Máiz, R M Girón, A Solé, M Martínez, S Quirós

Affiliation

¹ Unit of Cystic Fibrosis and Bronchiectasis, Pulmonology Service, La Paz Universitary Hospital, Madrid, Spain.

Abstract

Background and aims: To specify the prevalence of patients diagnosed with CF at age of ≥60 year-old and to analyze their characteristics.

Patients and methods: Observational study of CF patients which were diagnosed at age ≥60 year-old. The analyzed variables were: age, sex, nationality, lung function parameters, conditions present at diagnosis, microbiological characteristics and genetic findings.

Results: eight patients were included. 7 patients were female (87.5%) with a mean age of 70.6 years (median 71.5 years, range 60-78 years). The most important findings were: sweat test >60 mEq/l; heterozygotes F508del; bronchiectasis in CT; methicillin-sensitive Staphylococcus aureus (50%) in sputum. The most patients presented a normal or mild obstructive lung function.

Conclusions: CF must also be considered a disease diagnosed in adulthood, incorporating the sweat test within the usual techniques of differential diagnosis in patients with different diseases associated with CF, because genetic counselling is esencial.

Keywords: Aging; Cystic fibrosis.

Publication types

Case Reports