Beta2 integrins are required for follicular helper T cell differentiation in humans

Clin Immunol. 2017 Jul:180:60-62. doi: 10.1016/j.clim.2017.04.002. Epub 2017 Apr 6.
No abstract available

Keywords: Beta2 integrins; CD18; CD18 deficiency; Follicular helper T cells (Tfh); Follicular regulatory T cells (Tfr); LAD-1.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • CD18 Antigens / genetics
  • CD18 Antigens / immunology*
  • Cell Differentiation / genetics
  • Cell Differentiation / immunology
  • Child
  • Germinal Center / immunology
  • Humans
  • Leukocyte-Adhesion Deficiency Syndrome / genetics
  • Leukocyte-Adhesion Deficiency Syndrome / immunology*
  • Male
  • Mutation, Missense
  • T-Lymphocytes, Helper-Inducer / immunology*
  • T-Lymphocytes, Regulatory / immunology*

Substances

  • CD18 Antigens

Supplementary concepts

  • Leukocyte adhesion deficiency type 1