Ipsilateral Pupillary Dilation Following Carotid Endarterectomy: A Temporary and Benign Phenomenon

Neurosurgery. 2017 May 1;80(5):E239-E244. doi: 10.1093/neuros/nyx051.

Abstract

Background and importance: Cases of post carotid endarterectomy (CEA) Horner's syndrome have been reported, with symptoms attributed to manipulation of the sympathetic plexus situated along the carotid artery; however, these patients presented with the typical constricted pupil. We report the first 3 cases to our knowledge of mydriasis following CEA.

Clinical presentation: We present 3 cases of CEA followed by immediate postoperative development of ipsilateral mydriasis. The patients were otherwise at their neurologic baseline and the mydriasis resolved over the ensuing few days.

Conclusion: We suggest that these cases are secondary to an ischemic phenomenon, specifically to parasympathetic structures such as the ciliary ganglion and/or oculomotor nerve, resulting in autonomic dysfunction manifested by pupillary dilation. A similar finding of mydriasis occurring subsequent to other carotid pathology has been reported, with ischemia to parasympathetic structures also proposed as the underlying etiology. Although pupillary dilation often represents a worrisome neurosurgical sign indicating herniation, it should be recognized that after CEA this finding may be a transient, benign occurrence.

Keywords: Carotid endarterectomy; Mydriasis; Nerve ischemia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carotid Artery, Common / diagnostic imaging
  • Carotid Artery, Common / surgery
  • Carotid Artery, Internal / diagnostic imaging
  • Carotid Artery, Internal / surgery
  • Carotid Stenosis / diagnostic imaging*
  • Carotid Stenosis / surgery*
  • Dilatation
  • Endarterectomy, Carotid / adverse effects*
  • Endarterectomy, Carotid / trends
  • Humans
  • Male
  • Middle Aged
  • Mydriasis / diagnostic imaging*
  • Mydriasis / etiology*