Polymer sutures for simultaneous wound healing and drug delivery - A review

Int J Pharm. 2017 May 30;524(1-2):454-466. doi: 10.1016/j.ijpharm.2017.03.041. Epub 2017 Apr 4.

Abstract

Drug delivery using suitable polymeric devices has gathered momentum in the recent years due to their remarkable properties. The versatility of polymeric materials makes them reliable candidates for site targeted drug release. Among them biodegradable sutures has received considerable attention because they offer great promises in the realm of drug delivery. Sutures have been found to be an effective strategy for the delivery of antibacterial agents or anti-inflammatory drugs to the surgical site. Recent developments yielded sutures with improved mechanical properties, but designing sutures with all the desirable properties is still under investigation. This review is an attempt to analyze the recent developments pertaining to biologically active sutures emphasizing their potential as drug delivery vehicle.

Keywords: Antibacterial; Biodegradable; Drug delivery; Scaffolds; Sutures.

Publication types

  • Review

MeSH terms

  • Drug Delivery Systems*
  • Drug Liberation
  • Humans
  • Polymers
  • Sutures*
  • Wound Healing*

Substances

  • Polymers