Abstract
An aggregation induced emission (AIE) based bioimaging probe, TPE-Gal, was designed for light-up imaging of β-galactosidase in living cells. The applicability of TPE-Gal in imaging endogenous β-galactosidase activity was confirmed in OVCAR-3 cells.
MeSH terms
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Cell Line, Tumor
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Cell Survival
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Dose-Response Relationship, Drug
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Female
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Fluorescent Dyes / analysis
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Fluorescent Dyes / chemistry*
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Galactose / pharmacology
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HeLa Cells
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Humans
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Light*
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Molecular Structure
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Optical Imaging*
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Ovarian Neoplasms / diagnostic imaging*
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Ovarian Neoplasms / drug therapy*
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Ovarian Neoplasms / metabolism
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Spectrometry, Fluorescence
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Stilbenes / chemistry*
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Structure-Activity Relationship
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beta-Galactosidase / analysis*
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beta-Galactosidase / metabolism
Substances
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Fluorescent Dyes
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Stilbenes
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tetraphenylethylene
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beta-Galactosidase
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Galactose