Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis

Federico R Laham; Jonathan M Mansbach; Pedro A Piedra; Kohei Hasegawa; Ashley F Sullivan; Janice A Espinola; Carlos A Camargo Jr

doi:10.1097/INF.0000000000001596

Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis

Pediatr Infect Dis J. 2017 Aug;36(8):808-810. doi: 10.1097/INF.0000000000001596.

Authors

Federico R Laham¹, Jonathan M Mansbach, Pedro A Piedra, Kohei Hasegawa, Ashley F Sullivan, Janice A Espinola, Carlos A Camargo Jr

Affiliation

¹ From the *Department of Pediatric Infectious Diseases, Arnold Palmer Hospital for Children, Orlando, Florida; †Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts; ‡Departments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas; and §Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Abstract

In this analysis of a prospective, multicenter study of children hospitalized with bronchiolitis, 925 had respiratory syncytial virus (RSV)-A and 649 had RSV-B. Overall, bronchiolitis severity did not differ by RSV subtype. However, among children with RSV-only bronchiolitis, those children with RSV-A had higher risk of intensive care treatment (odds ratio, 1.31; 95% confidence interval, 1.00-1.71; P = 0.048) when compared with those having RSV-B.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Bronchiolitis* / epidemiology
Bronchiolitis* / physiopathology
Bronchiolitis* / virology
Female
Humans
Infant
Length of Stay
Male
Prospective Studies
Respiratory Syncytial Virus Infections* / epidemiology
Respiratory Syncytial Virus Infections* / physiopathology
Respiratory Syncytial Virus Infections* / virology
Respiratory Syncytial Virus, Human*

Grants and funding

U01 AI067693/AI/NIAID NIH HHS/United States