Pulmonary sequestration (SP), is a rare condition, which requires a high index of suspicion for appropriate diagnosis. Clinical manifestations usually simulate banal respiratory diseases, so the diagnosis always tends to be delayed. Surgical treatment by video-assisted, thoracic surgery is a safe option for the management of pulmonary sequestration. The extensive evaluation of the images and knowledge of certain anatomical details are necessary to prevent accidents during surgery. Surgery at an early age helps surgical resection with fewer complications. Here are three cases of SP, which demonstrate clear and simple forms of presentation of the pathology and surgical management by our group in treating it.