The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome

Funda Erbasan; Yesim Cekin; Deniz Turgut Coban; Ugur Karasu; Dinc Suren; Ayhan H Cekin

doi:10.12669/pjms.331.11168

The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome

Pak J Med Sci. 2017 Jan-Feb;33(1):137-141. doi: 10.12669/pjms.331.11168.

Authors

Funda Erbasan¹, Yesim Cekin², Deniz Turgut Coban³, Ugur Karasu⁴, Dinc Suren⁵, Ayhan H Cekin⁶

Affiliations

¹ Funda Erbasan, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
² Yesim Cekin, MD. Associate Professor, Department of Microbiology, Antalya Training and Research Hospital, Antalya, Turkey.
³ Deniz Turgut Coban, MD. Specialist, Department of Ophthalmology, Antalya Training and Research Hospital, Antalya, Turkey.
⁴ Ugur Karasu, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
⁵ Dinc Suren, MD. Associate Professor, Department of Pathology, Antalya Training and Research Hospital, Antalya, Turkey.
⁶ Ayhan H. Cekin, MD. Associate Professor, Department of Gastroenterology, Antalya Training and Research Hospital, Antalya, Turkey.

Abstract

Objective: To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).

Methods: Seventy seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed. And the diagnosis of SS was made according to the American College of Rheumatology (ACR) classification criteria for SS - 2012.

Results: Thirteen (16.9%) of IBS patients had FM. Dry eye was detected in 20(26.0%), 7(9.1%) and 29(37.7%) patients by OSS, Schirmer test and TBUT, respectively. Of 77 patients with IBS, the diagnosis of SS was established in two patients (2.6%).

Conclusion: The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.

Keywords: Antinuclear antibodies; Fibromyalgia; Irritable Bowel Syndrome; Sjogren’s Syndrome.