Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape
Leukemia
.
2017 Jul;31(7):1640-1644.
doi: 10.1038/leu.2017.109.
Epub 2017 Apr 3.
Authors
P Silva
1
,
M Neumann
1
2
3
,
M P Schroeder
1
,
S Vosberg
2
3
4
,
C Schlee
1
,
K Isaakidis
1
,
J Ortiz-Tanchez
1
,
L R Fransecky
1
,
T Hartung
1
,
S Türkmen
5
6
,
A Graf
7
,
S Krebs
7
,
H Blum
7
,
C Müller-Tidow
8
,
C Thiede
2
3
9
,
G Ehninger
2
3
9
,
H Serve
2
3
10
,
J Hecht
11
12
,
W E Berdel
13
,
P A Greif
2
3
4
,
C Röllig
2
3
9
,
C D Baldus
1
2
3
Affiliations
1
Department of Hematology and Oncology, Charité University Hospital, Berlin, Germany.
2
German Cancer Consortium (DKTK), Heidelberg, Germany.
3
German Cancer Research Center (DKFZ), Heidelberg, Germany.
4
Department of Internal Medicine 3, Ludwig Maximilians University, Munich, Germany.
5
Labor Berlin Charité Vivantes GmbH, Berlin, Germany.
6
Institute of Medical Genetics and Human Genetics, Charité University Medicine, Campus Virchow-Klinikum, Berlin, Germany.
7
Laboratory for Functional Genome Analysis, Gene Center, Ludwig Maximilians University, Munich, Germany.
8
Department of Medicine IV, Hematology and Oncology, University Hospital of Halle (Saale), Halle, Germany.
9
Department of Internal Medicine I, University Hospital Carl-Gustav-Carus, Dresden, Germany.
10
Department of Medicine II, Hematology/Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany.
11
Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
12
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
13
Department of Medicine A, University Hospital Münster, Münster, Germany.
PMID:
28366934
DOI:
10.1038/leu.2017.109
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Aged
Aged, 80 and over
Epigenesis, Genetic*
Humans
Leukemia, Myeloid, Acute / genetics*