Role of Angiography in Systemic Lupus Erythematosus-Induced Choroiditis

Ocul Immunol Inflamm. 2018;26(8):1146-1149. doi: 10.1080/09273948.2017.1298821. Epub 2017 Mar 31.

Abstract

Purpose: To report a case of systemic lupus erythematosus-induced choroidal vasculitis.

Methods: A 34-year-old woman with a long-standing history of systemic lupus erythematosus had a sudden painless loss of vision in the right eye over 12 hours. Ocular examination revealed a visual acuity of counting fingers of 1 foot on the right eye and 20/20 on the left. There was a relative afferent pupillary defect on the right side with a pink, distinct optic disk margin.

Results: Optical coherence tomography of the macula and fundus fluorescein angiogram for the eyes were normal. The MRI brain and orbit with the cerebral MRA did not show signs of optic neuritis or occipital vasculitic changes. However, the indocyanine green angiography revealed patches of ill-defined areas of choroidal hypofluorescence in the early- to mid-phase in the macula region.

Conclusion: ICGA becomes the crucial tool in unmasking the presence of choroidal vasculitis.

Keywords: Choroidal Vasculitis; Choroiditis; Choroidopathy; Indocyanine Green Angiography (ICGA); Systemic Lupus Erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Choroiditis / diagnosis*
  • Choroiditis / drug therapy
  • Coloring Agents / administration & dosage
  • Female
  • Fluorescein Angiography*
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Indocyanine Green / administration & dosage
  • Infusions, Intravenous
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / drug therapy
  • Magnetic Resonance Imaging
  • Methylprednisolone / therapeutic use
  • Prednisolone / therapeutic use
  • Tomography, Optical Coherence
  • Vision Disorders / diagnosis*
  • Vision Disorders / drug therapy
  • Visual Acuity

Substances

  • Coloring Agents
  • Glucocorticoids
  • Immunoglobulins, Intravenous
  • Prednisolone
  • Indocyanine Green
  • Methylprednisolone