Epilepsy: Is there hope?

Indian J Med Res. 2016 Nov;144(5):657-660. doi: 10.4103/ijmr.IJMR_1051_16.

Abstract

Epilepsy is a highly prevalent chronic neurologic disorder and leads to social, behavioural, health and economic consequences. 'Treatment gap' varies from 10 per cent in developed countries to 75 per cent in low-income countries. Stigma and discrimination related to epilepsy are prevalent worldwide. Electroencephalography (EEG) is considered the most important tool for evaluating the patient with epilepsy. Video-EEG monitoring is an important tool for confirming the seizure type and estimating the epileptogenic zone in the brain. Neuroimaging evaluation is important to determine the aetiology of the epilepsies. Genetic testing has increased the probability of identifying the causes of some types of epilepsies. Epilepsy can be treated in an affordable way with low-cost medications. Refractory epilepsies occur in approximately one-third of recently diagnosed patients with epilepsy. For this group of patients, there are options of surgical treatment, diets and neurostimulation to improve seizure control and quality of life. In poorly organized societies, there is a lack of prioritization of epilepsy in national health policies, limited resources for trained personnel and a shortage of basic antiepileptic medications. There is evidence of improvement in the understanding of epilepsy and a clear progress in the management of epileptic seizures in recent times.

Publication types

  • Review

MeSH terms

  • Anticonvulsants / therapeutic use*
  • Electroencephalography
  • Epilepsy / diagnosis
  • Epilepsy / drug therapy*
  • Epilepsy / genetics
  • Epilepsy / physiopathology*
  • Humans
  • Seizures / diagnosis
  • Seizures / drug therapy
  • Seizures / physiopathology*

Substances

  • Anticonvulsants