Bioconversion of lutein by Enterobacter hormaechei to form a new compound, 8-methyl-α-ionone

Biotechnol Lett. 2017 Jul;39(7):1019-1024. doi: 10.1007/s10529-017-2329-y. Epub 2017 Mar 28.

Abstract

Objectives: To investigate the final product of the bioconversion of lutein by a novel lutein-degrading bacterium, Enterobacter hormaechei A20, and the kinetics of the process.

Results: A new product, 8-methyl-α-ionone, was resolved by GC-MS. The compound was further identified by NMR. A conversion yield of 90% was achieved by E. hormaechei in 36 h with 10 g lutein l-1.

Conclusions: This is the first report of the bioconversion of lutein to form 8-methyl-α-ionone. A degradation pathway is proposed.

Keywords: 8-Methyl-α-ionone; Bioconversion; Enterobacter hormaechei; Lutein.

MeSH terms

  • Biotransformation*
  • Enterobacter / metabolism*
  • Gas Chromatography-Mass Spectrometry
  • Lutein / metabolism*
  • Metabolic Networks and Pathways
  • Norisoprenoids / metabolism*
  • Time Factors

Substances

  • 8-methyl-alpha-ionone
  • Norisoprenoids
  • Lutein