Cariogenic Potential of the commonly Prescribed Pediatric Liquid Medicaments in Kingdom of Saudi Arabia: An in vitro Study

J Contemp Dent Pract. 2017 Apr 1;18(4):307-311. doi: 10.5005/jp-journals-10024-2036.

Abstract

Aim: The aim of this study was to assess the cariogenic potential of the commonly prescribed pediatric liquid medicaments (PLMs) for dental disease in Jazan region, Kingdom of Saudi Arabia.

Materials and methods: Seven most commonly prescribed PLMs were selected by prior questioning the pediatric dentists as well as general dentists in Jazan region. The endogenous pH and sucrose concentrations of the liquid medicaments were assessed. The endogenous pH was assessed by Hanna pH meter instrument. The sucrose concentration was assessed by anthrone reagent method.

Results: All the PLM were acidic. The pH of the PLM ranged from 4.22 to 6.10. All the PLM contained sucrose and its concentration ranged from 5.38 to 11.41 gm% in the samples.

Conclusion: In this study, all the PLM were acidic and contained sucrose. Hence, they have cariogenic potential.

Clinical significance: Parents and dentists are unaware of the hidden sugars and cariogenicity of these medications. Strict oral hygiene instructions are mandatory for the children taking these medications. The use of PLM should also be minimized and parents should seek early dental treatment to restore child's oral health.

Keywords: Cariogenicity; Pediatric liquid medicaments; pH Sucrose..

MeSH terms

  • Cariogenic Agents / administration & dosage
  • Cariogenic Agents / adverse effects*
  • Child
  • Drug-Related Side Effects and Adverse Reactions / etiology*
  • Humans
  • Hydrogen-Ion Concentration
  • In Vitro Techniques
  • Pharmaceutical Preparations / administration & dosage*
  • Saudi Arabia
  • Solutions / adverse effects*
  • Solutions / chemistry
  • Sucrose / adverse effects
  • Sucrose / analysis

Substances

  • Cariogenic Agents
  • Pharmaceutical Preparations
  • Solutions
  • Sucrose