Whole-genome Sequencing of Vibrio sinaloensis T47, a Tropical Marine Isolate with Quorum Sensing Properties

Nur Izzati Mohamad; Kah Yan How; Wai-Fong Yin; Kok-Gan Chan

doi:10.7150/jgen.16163

Whole-genome Sequencing of Vibrio sinaloensis T47, a Tropical Marine Isolate with Quorum Sensing Properties

J Genomics. 2017 Mar 9:5:48-50. doi: 10.7150/jgen.16163. eCollection 2017.

Authors

Nur Izzati Mohamad¹, Kah Yan How¹, Wai-Fong Yin¹, Kok-Gan Chan¹

Affiliation

¹ Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, 50603 Malaysia.

Abstract

A large number of Vibrio sp. thrive in the marine environment and they are notable to cause food borne infection associated with undercooked seafood. In this study, we report the whole genome sequence of Vibrio sinaloensis T47 which was isolated from coastal marine water in Morib Beach, Hulu Selangor. The genome is made up of approximately 4.59 Mbp with 80 contigs and 46% G+C content. From the annotated genome, genes associated with quorum sensing (QS) were identified. This research provides a genetic basis for better understanding of QS pathway which contributes to the physiological traits of strain T47 to thrive in the marine environment.

Keywords: Vibrio sinaloensis; autoinducer synthase; quorum sensing; virulence factor; whole genome sequencing.