Supraclavicular lymph node metastases from malignant gastrointestinal stromal tumor of the jejunum: A case report with review of the literature

World J Gastroenterol. 2017 Mar 14;23(10):1920-1924. doi: 10.3748/wjg.v23.i10.1920.

Abstract

Gastrointestinal stromal tumors (GISTs) represent the most common mesenchymal tumors of the alimentary tract. These tumors may have different clinical and biological behaviors. Malignant forms usually spread via a hematogenous route, and lymph node metastases rarely occur. Herein, we report a patient with a jejunal GIST who developed supraclavicular lymph node metastasis. We conclude that lymphatic diffusion via the mediastinal lymphatic station to the supraclavicular lymph nodes can be a potential metastatic route for GISTs.

Keywords: Gastrointestinal stromal tumor; Lymph nodes; Metastasis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Biopsy, Needle
  • Chemotherapy, Adjuvant
  • Erythrocyte Transfusion
  • Gastrointestinal Stromal Tumors / complications*
  • Gastrointestinal Stromal Tumors / diagnosis
  • Gastrointestinal Stromal Tumors / pathology*
  • Gastrointestinal Stromal Tumors / therapy
  • Humans
  • Imatinib Mesylate / administration & dosage
  • Imatinib Mesylate / therapeutic use
  • Jejunum / pathology
  • Jejunum / surgery
  • Lymph Nodes / pathology
  • Lymphatic Metastasis
  • Male
  • Melena / etiology*
  • Melena / therapy
  • Middle Aged
  • Neck Dissection
  • Neoplasm Grading
  • Positron Emission Tomography Computed Tomography
  • Stomach Neoplasms / complications*
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / therapy
  • Ultrasonography

Substances

  • Antineoplastic Agents
  • Imatinib Mesylate