Post-Traumatic Sleep-Wake Disorders

Curr Neurol Neurosci Rep. 2017 Apr;17(4):38. doi: 10.1007/s11910-017-0744-z.

Abstract

All living organisms that face a traumatic life event are susceptible to sleep-wake disturbances. Stress, which can result in trauma, evokes a high level of physiological arousal associated with sympathetic nervous system activation, during both sleep and wakefulness. Heredity, sex hormones, early losses, developmental factors and intra- and interpersonal conflicts, contribute to the level of baseline physiological arousal, producing either subclinical, clinical or complex clinical traits, acutely and at any time after exposure to a traumatic event. The risk of acute sleep-wake disturbances becoming disorders and syndromes depends on the type of traumatic event and all of the aforementioned factors. Taken together, with consideration for behavioural and environmental heterogeneity, in research, will aid identification and understanding of susceptibility factors in long-term sleep and wakefulness pathology after exposure to traumatic events.

Keywords: Disorders of sleep and wakefulness; Hyperarousal; Risk; Sex differences; Trauma.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain Injuries, Traumatic / complications
  • Humans
  • Sex Characteristics
  • Sleep / physiology
  • Sleep Wake Disorders / etiology*
  • Stress, Psychological / complications*
  • Wakefulness / physiology

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