Pulsed-Dose Rate Brachytherapy for the Treatment of Endometrial Cancer

Francesca De Felice; Rossella Caiazzo; Ilaria Benevento; Daniela Musio; Filippo Rubini; Vincenzo Tombolini

doi:10.1159/000461584

Pulsed-Dose Rate Brachytherapy for the Treatment of Endometrial Cancer

Oncology. 2017;92(6):311-316. doi: 10.1159/000461584. Epub 2017 Mar 24.

Authors

Francesca De Felice¹, Rossella Caiazzo, Ilaria Benevento, Daniela Musio, Filippo Rubini, Vincenzo Tombolini

Affiliation

¹ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.

PMID: 28334713
DOI: 10.1159/000461584

Abstract

Endometrial cancer (EC) is the most frequent gynecologic malignancy. The aim of this review is to outline clinical practice recommendations, to suggest a technical solution, and to advise doses selection for pulsed-dose rate (PDR) brachytherapy in EC. Electronic bibliographic databases, including PubMed, clinicaltrials.gov, and the American Society of Clinical Oncology (ASCO) Meeting Library, were searched for articles in English. Clinical guidelines and systematic reviews were also considered. The appropriate therapeutic approach should consider risk factors for tumor relapse and PDR brachytherapy and have a convincing role in this multidisciplinary scenario. Performing PDR brachytherapy in EC requires robust training and experience.

Keywords: Adjuvant treatment; Brachytherapy; Endometrial cancer; Pulsed-dose rate; Radiotherapy.

Publication types

Review

MeSH terms

Brachytherapy* / methods
Endometrial Neoplasms / pathology
Endometrial Neoplasms / radiotherapy*
Female
Humans
Neoplasm Recurrence, Local / prevention & control*
Practice Guidelines as Topic
Radiotherapy Dosage
Radiotherapy, Adjuvant / methods
Radiotherapy, Intensity-Modulated / methods