Social and Clinical Characteristics of Immigrants with Tuberculosis in South Korea

Yonsei Med J. 2017 May;58(3):592-597. doi: 10.3349/ymj.2017.58.3.592.

Abstract

Purpose: To determine the social and clinical characteristics of immigrants with tuberculosis (TB) in South Korea.

Materials and methods: The registered adult TB patients who were diagnosed and treated in Korea Medical Centers from January 2013 to December 2015 were analyzed retrospectively. A total of 105 immigrants with TB were compared to 932 native Korean TB patients.

Results: Among these 105 immigrants with TB, 86 (82%) were Korean-Chinese. The rate of drug-susceptible TB were lower in the immigrants group than in the native Korean group [odds ratio (OR): 0.46; 95% confidence interval (CI): 0.22-0.96, p=0.035]. Cure rate was higher in the immigrant group than in the native Korean group (OR: 2.03; 95% CI: 1.26-3.28, p=0.003). Treatment completion rate was lower in the immigrant group than in the native Korean group (OR: 0.50; 95% CI: 0.33-0.74, p=0.001). However, treatment success rate showed no significant difference between two groups (p=0.141). Lost to follow up (default) rate was higher in the immigrant group than in the native Korean group after adjusting for age and drug resistance (OR: 3.61; 95% CI: 1.36-9.61, p=0.010). There was no difference between defaulter and non-defaulter in clinical characteristics or types of visa among these immigrants (null p value). However, 43 TB patients with recent immigration were diagnosed as TB even though they had been screened as normal at the time of immigration.

Conclusion: Endeavor to reduce the default rate of immigrants with TB and reinforce TB screening during the immigration process must be performed for TB infection control in South Korea.

Keywords: Immigrants; mass screening; medication adherence; microbial sensitivity tests; tuberculosis.

MeSH terms

  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use*
  • Emigrants and Immigrants* / psychology
  • Emigrants and Immigrants* / statistics & numerical data
  • Female
  • Humans
  • Male
  • Mass Screening / statistics & numerical data
  • Medication Adherence*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Odds Ratio
  • Republic of Korea / epidemiology
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Tuberculosis / diagnosis
  • Tuberculosis / drug therapy*
  • Tuberculosis / ethnology*

Substances

  • Antitubercular Agents