Abstract
We conducted a study in Binh Phuoc, Vietnam, in 2015 on the therapeutic efficacy of dihydroartemisinin/piperaquine for Plasmodium falciparum malaria. A high number of treatment failures (14/40) was found, and piperaquine resistance in Vietnam was confirmed. A change in the malaria treatment policy for Vietnam is in process.
Keywords:
Plasmodium falciparum; Vietnam; antimicrobial resistance; artemisinin; dihydroartemisinin/piperaquine; drug resistance; malaria; mefloquine; piperaquine; vector-borne infections.
MeSH terms
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Adolescent
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Adult
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Antimalarials / administration & dosage
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Antimalarials / therapeutic use*
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Artemisinins / administration & dosage
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Artemisinins / therapeutic use*
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Drug Combinations
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Drug Resistance*
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Female
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Humans
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Malaria, Falciparum / drug therapy*
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Malaria, Falciparum / epidemiology
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Male
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Middle Aged
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Mutation
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Plasmodium falciparum / genetics
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Protozoan Proteins / genetics
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Protozoan Proteins / metabolism
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Quinolines / administration & dosage
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Quinolines / therapeutic use*
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Vietnam / epidemiology
Substances
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Antimalarials
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Artemisinins
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Drug Combinations
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Protozoan Proteins
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Quinolines
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artenimol
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piperaquine