Study of light scattering using C-Quant® in patients with Fuchs' endothelial dystrophy: A pilot study

Abstract

Objective: The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters.

Materials and methods: The values of light scattering were measured by C-Quant^® (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema. Corneal biomechanical properties were determined using ORA (ocular response) and Corvis ST^® (tonometry).

Results: A light scattering value outside the normal range was observed in 93.8% of eyes studied. No statistically significant association (P>.05) was found between the values of the measured light scattering by C-Quant^® and endothelial count, pachymetry, or corneal biomechanical properties.

Conclusions: In this study, changes were found in the values of light scattering values of patients with corneal Fuchs' endothelial dystrophy. This change does not appear to correlate significantly with disease severity.

Keywords: C-Quant(®); Corneal biomechanical properties; Difusión de la luz; Distrofia endotelial de Fuchs; Fuchs’ endothelial dystrophy; Light scattering; Propiedades biomecánicas corneales.