Activation of SF6 at Platinum Complexes: Formation of SF3 Derivatives and Their Application in Deoxyfluorination Reactions

Claudia Berg; Thomas Braun; Mike Ahrens; Philipp Wittwer; Roy Herrmann

doi:10.1002/anie.201612417

Activation of SF₆ at Platinum Complexes: Formation of SF₃ Derivatives and Their Application in Deoxyfluorination Reactions

Angew Chem Int Ed Engl. 2017 Apr 3;56(15):4300-4304. doi: 10.1002/anie.201612417. Epub 2017 Mar 20.

Authors

Claudia Berg¹, Thomas Braun¹, Mike Ahrens¹, Philipp Wittwer¹, Roy Herrmann¹

Affiliation

¹ Department of Chemistry, Humboldt-Universität zu Berlin, Brook-Taylor-Strasse 2, 12489, Berlin, Germany.

PMID: 28319294
DOI: 10.1002/anie.201612417

Abstract

The activation of SF₆ at [Pt(PR₃ )₂ ] R=Cy, iPr complexes in the presence of PR₃ led selectively and in an unprecedented reaction route to the generation of the SF₃ complexes trans-[Pt(F)(SF₃ )(PR₃ )₂ ]. These can also be synthesized from SF₄ and the SF₂ derivative trans-[Pt(F)(SF₂ )(PCy₃ )₂ ][BF₄ ] was characterized by X-ray crystallography. trans-[Pt(F)(SF₃ )(PR₃ )₂ ] complexes are useful tools for deoxyfluorination reactions and novel fluorido complexes bearing a SOF ligand are formed. Based on these studies a process for the deoxyfluorination of ketones was developed with SF₆ as fluorinating agent.

Keywords: S−F activation; fluorination; fluorine; platinum; sulfurhexafluoride.

Publication types

Research Support, Non-U.S. Gov't