Updated recommendations on the use of hydroxychloroquine in dermatologic practice

Abstract

Hydroxychloroquine has unique immunomodulatory properties and an attractive adverse effect profile. Over the past 10 years, research has led to significant updates in clinical recommendations concerning the optimal use of hydroxychloroquine and monitoring of patients taking it. We discuss updated recommendations concerning hydroxychloroquine daily dosing, retinopathy screening, serologic monitoring, use in smokers, use in pregnant women, and adverse effect risk and monitoring. This review can hopefully serve as an aid to dermatologists and help ensure they continue using hydroxychloroquine safely and effectively.

Keywords: adverse effects; hydroxychloroquine; lupus erythematosus; monitoring; recommendations; retinopathy screening; whole blood levels.