Twenty-five Years of DNA-Encoded Chemical Libraries

Dario Neri

doi:10.1002/cbic.201700130

Twenty-five Years of DNA-Encoded Chemical Libraries

Chembiochem. 2017 May 4;18(9):827-828. doi: 10.1002/cbic.201700130. Epub 2017 Mar 20.

Author

Dario Neri¹

Affiliation

¹ Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, ETH Zürich), ETH Hoenggerberg, HCI G392.4, Vladimir Prelog Weg 4, 8093, Zürich, Switzerland.

PMID: 28318088
DOI: 10.1002/cbic.201700130

Abstract

Reference library: The availability of DNA-encoded chemical libraries containing billions of compounds facilitates the discovery of binding molecules for pharmaceutical applications and for investigating biological processes. This Special Issue highlights the use of this library technology and some of the latest developments in the field.

Keywords: DNA; chemical libraries; drug development; drug discovery.

Publication types

Editorial

MeSH terms

DNA / chemistry*
DNA / metabolism
Drug Discovery
Peptide Library
Protein Kinase Inhibitors / chemistry
Small Molecule Libraries / chemistry*

Substances

Peptide Library
Protein Kinase Inhibitors
Small Molecule Libraries
DNA