Evaluation of Patients with Sinonasal and Ventral Skull Base Malignancies

Otolaryngol Clin North Am. 2017 Apr;50(2):221-244. doi: 10.1016/j.otc.2016.12.002.

Abstract

A wide variety of tumors present in the sinonasal and ventral skull base. Patients often have nonspecific symptoms initially and present with advanced tumors, affecting the orbit and other adjacent structures. Evaluation of these malignancies with modern imaging techniques can define tumor invasion, but biopsy is often required to establish a diagnosis because most have a nonspecific appearance. A thorough understanding of the anatomy is the key to treatment planning, and a multidisciplinary approach determines the optimal strategy.

Keywords: Histology; Imaging; Office examination; Pathology; Skull base; Tumors.

Publication types

  • Review

MeSH terms

  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Neoplasm Grading
  • Neoplasm Staging
  • Nose Neoplasms / classification
  • Nose Neoplasms / diagnostic imaging*
  • Nose Neoplasms / pathology*
  • Orbit / pathology
  • Skull Base / pathology
  • Skull Base Neoplasms / classification
  • Skull Base Neoplasms / diagnostic imaging*
  • Skull Base Neoplasms / pathology*
  • Tomography, X-Ray Computed
  • Treatment Outcome