Abstract
A new cyclic diarylheptanoid (1) and a new flavone glucoside (2), along with seven known compounds, were isolated from the green peel of Juglans mandshurica. Their structures were elucidated based on extensive spectroscopic analyses. Moreover, the cytotoxicity against NCI-H460, A549, and K562 cancer cells of compounds 1-6 was evaluated. The results showed that compound 3 exhibited moderate inhibitory potency against the growth of three cell lines.
Keywords:
Juglans mandshurica; cytotoxicity; diarylheptanoid; flavone glycoside.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Diarylheptanoids / chemistry
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Diarylheptanoids / isolation & purification*
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Diarylheptanoids / pharmacology
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Drug Screening Assays, Antitumor
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Flavones / chemistry
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Flavones / isolation & purification*
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Flavones / pharmacology
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Glucosides / chemistry
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Glucosides / isolation & purification*
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Glucosides / pharmacology
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Hep G2 Cells
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Humans
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Juglans / chemistry*
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K562 Cells
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Molecular Structure
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Plant Extracts / chemistry
Substances
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Antineoplastic Agents, Phytogenic
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Diarylheptanoids
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Drugs, Chinese Herbal
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Flavones
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Glucosides
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Plant Extracts
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juglanin D
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rhamnetin-3-O-beta-D-xylopyranoside