Purpose: To report a case of congenital retinal macrovessels associated with cystoid macular edema.
Methods: We evaluated a 33-year-old, 2-month pregnant female with sudden decreased central vision in her left eye.
Results: We observed congenital retinal venous macrovessels that were related to cystoid macular edema development. After 3 months, her clinical condition improved with a spontaneous solution of the edema and visual acuity recovery.
Conclusion: Congenital retinal macrovessels can be complicated by macular edema. The high levels of hormones during pregnancy can affect the vessels' permeability and make this condition symptomatic through cystoid macular edema development.