Host-guest complexation of cucurbit[8]uril with two enantiomers

Zhong-Zheng Gao; Rui-Lian Lin; Dong Bai; Zhu Tao; Jing-Xin Liu; Xin Xiao

doi:10.1038/srep44717

Host-guest complexation of cucurbit[8]uril with two enantiomers

Sci Rep. 2017 Mar 16:7:44717. doi: 10.1038/srep44717.

Authors

Zhong-Zheng Gao¹, Rui-Lian Lin², Dong Bai¹, Zhu Tao¹, Jing-Xin Liu², Xin Xiao¹

Affiliations

¹ Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang 550025, P. R. China.
² College of Chemistry and Chemical Engineering, Anhui University of Technology, Maanshan 243002, P. R. China.

Abstract

Host-guest complexation of cucurbit[8]uril (Q[8]) with two enantiomers, D-3-(2-naphthyl)-alanine (D-NA) and L-3-(2-naphthyl)-alanine (L-NA), has been fully investigated. Experimental data indicate that double guests reside within the cavity of Q[8] in both aqueous solution and solid state, generating highly stable homoternary complexes D-NA₂@Q[8] and L-NA₂@Q[8].

Publication types

Research Support, Non-U.S. Gov't