Iron-Catalyzed gem-Specific Dimerization of Terminal Alkynes

Qiuming Liang; Kimberly M Osten; Datong Song

doi:10.1002/anie.201700904

Iron-Catalyzed gem-Specific Dimerization of Terminal Alkynes

Angew Chem Int Ed Engl. 2017 May 22;56(22):6317-6320. doi: 10.1002/anie.201700904. Epub 2017 Mar 13.

Authors

Qiuming Liang¹, Kimberly M Osten¹, Datong Song¹

Affiliation

¹ Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada.

PMID: 28295865
DOI: 10.1002/anie.201700904

Abstract

We report a gem-specific homo- and cross-dimerization of terminal alkynes catalyzed by a well-defined iron(II) complex containing Cp* and picolyl N-heterocyclic carbene (NHC) ligands, and featuring a piano-stool structure. This catalytic system requires no additives and is compatible with a broad range of substrates, including those with polar functional groups such as NH and OH.

Keywords: N-heterocyclic carbenes; alkynes; dimerization; homogeneous catalysis; iron.

Publication types

Research Support, Non-U.S. Gov't