RETRACTED: The effects of the long non-coding RNA MALAT-1 regulated autophagy-related signaling pathway on chemotherapy resistance in diffuse large B-cell lymphoma

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. An Expression of Concern for this article was previously published while an investigation was conducted (see related editorial: https://doi.org/10.1016/j.biopha.2022.113812). This retraction notice supersedes the Expression of Concern published earlier. Concern was raised about the reliability of the images in Figure 5B, and the Western blots shown in Figure 9A+B, which appear to contain similar repeated features, and a phenotype found in other publications, as detailed here: https://pubpeer.com/publications/81D7B72D646EC532D0DFF63338A55F; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. Independent analysis confirmed these findings and identified additional suspected image duplications in Figures 5A+B and 9A+B. The journal requested the corresponding author comment on these concerns and provide the associated raw data. The authors did not respond to this request and therefore the Editor-in-Chief decided to retract the article.

Keywords: Autophagy; Chemotherapy; Diffuse large B-cell lymphoma; Long non-coding RNA MALAT-1; Resistance; Signaling pathway.