Genome sequence and description of Anaeromassilibacillus senegalensis gen. nov., sp. nov., isolated from the gut of patient with kwashiorkor

E Guilhot; M T Alou; J-C Lagier; N Labas; C Couderc; J Delerce; A Diallo; C Sokhna; P-E Fournier; D Raoult; S Khelaifia

doi:10.1016/j.nmni.2017.01.009

Genome sequence and description of Anaeromassilibacillus senegalensis gen. nov., sp. nov., isolated from the gut of patient with kwashiorkor

New Microbes New Infect. 2017 Feb 2:17:54-64. doi: 10.1016/j.nmni.2017.01.009. eCollection 2017 May.

Authors

E Guilhot¹, M T Alou¹, J-C Lagier¹, N Labas¹, C Couderc¹, J Delerce¹, A Diallo², C Sokhna², P-E Fournier¹, D Raoult³, S Khelaifia¹

Affiliations

¹ Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes IRD 198, CNRS 7278, UM63, INSERM 1095, Aix-Marseille Université, Institut Hospitalo-Universitaire Méditerranée-Infection, Faculté de médecine, Marseille, France.
² Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes IRD 198, CNRS 7278, Aix-Marseille Université, Marseille, France; Campus Commun UCAD-IRD of Hann, Dakar, Senegal.
³ Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes IRD 198, CNRS 7278, UM63, INSERM 1095, Aix-Marseille Université, Institut Hospitalo-Universitaire Méditerranée-Infection, Faculté de médecine, Marseille, France; Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes IRD 198, CNRS 7278, Aix-Marseille Université, Marseille, France; Campus Commun UCAD-IRD of Hann, Dakar, Senegal; Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

Abstract

Using the culturomics strategy, a wide range of anaerobic bacteria was discovered including Anaeromassilibacillus senegalensis strain mt9^T (= CSUR P1511 = DSM 102954), isolated from the gut microbiota of a 1-year-old Senegalese patient with kwashiorkor. This Gram-negative strain is a strictly anaerobic, spore-forming rod motile by a polar flagellum. The 3 511 289 bp long genome of this strain contains 3046 protein-coding and 49 RNA genes, including 45 tRNA and four rRNA genes, and exhibits a G+C content of 52.94%. Here we describe the features of this organism, together with the complete genome sequence and annotation.

Keywords: Anaeromassilibacillus senegalensis; culturomics; genome; human gut; taxonogenomics.