Simultaneous Liver Transplantation and Sleeve Gastrectomy: Prohibitive Combination or a Necessity?

Obes Surg. 2017 May;27(5):1387-1390. doi: 10.1007/s11695-017-2634-5.

Abstract

Previously, many morbidly obese (MO) patients were denied liver transplantation (LT) because of the higher operative risk. However, nowadays, 5 and 10 years graft survival is the rule, and patients whose lives can be prolonged with LT are dying of obesity-related comorbidities. Recent experience suggests that weight reduction in MO liver transplant recipients would improve their long-term survival. The bariatric surgery before LT is contraindicated for patients with decompensated cirrhosis, while post-transplant intervention is associated with increased technical difficulty. We present our experience with three patients who underwent simultaneous liver transplantation and sleeve gastrectomy. After a median 13 months follow-up, all patients are alive, having normal allograft function and significant weight loss. Combined liver transplantation with simultaneous sleeve gastrectomy appears technically feasible and relatively safe in selected patients.

Keywords: Bariatric surgery; Liver cirrhosis; Liver transplantation; Non-alcoholic steatohepatitis; Sleeve gastrectomy.

MeSH terms

  • Comorbidity
  • Gastrectomy* / adverse effects
  • Gastrectomy* / methods
  • Humans
  • Liver Diseases* / complications
  • Liver Diseases* / surgery
  • Liver Transplantation* / adverse effects
  • Liver Transplantation* / methods
  • Obesity, Morbid* / complications
  • Obesity, Morbid* / surgery