Life-Saving Degeneracy in the Human Immune System

Cell Host Microbe. 2017 Mar 8;21(3):309-310. doi: 10.1016/j.chom.2017.02.018.

Abstract

Different human immune system components coordinate to ensure effective control of pathogens. Israel et al. (2017) examine the immune system of a patient with an inborn genetic error, presenting as impaired TLR signaling and staphylococcal disease, and uncover a beautiful example of degeneracy between innate and adaptive branches of immunity.

Keywords: human immunology; immunodeficiency; immunology; newborn immune system; pediatrics; systems immunology.

Publication types

  • Comment

MeSH terms

  • Humans
  • Immune System*
  • Immunity, Innate / immunology*
  • Signal Transduction