Abstract
Cassia grandis is used for the treatment of skin disorders, back pain, aches, etc. in Vietnamese traditional medicine. In this paper, phytochemicals of the leaves were investigated. A new naphthalene derivative (1, cassgranon D) and, seven known compounds rutin (2), afzelin (3), quercitrin (4), epicatechin (5), (-)-epiafzelechin (6), isoquercitrin (7) and aloe emodin (8) were isolated from the ethyl acetate and methanol extracts. Their structures were elucidated by spectral evidences (UV, IR, MS, 1H, 13C, DEPT, HSQC and HMBC NMR), as well as by comparing with published data.
Keywords:
Cassgranon D; Cassia grandis; naphthalene derivative.
MeSH terms
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Anthraquinones / chemistry
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Anthraquinones / isolation & purification
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Cassia / chemistry*
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Cassia / metabolism
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Magnetic Resonance Spectroscopy
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Mannosides / chemistry
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Mannosides / isolation & purification
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Methanol / chemistry
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Molecular Structure
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Naphthalenes / chemistry*
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Plant Extracts / chemistry
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Plant Leaves / chemistry*
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Plants, Medicinal / chemistry
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Proanthocyanidins / chemistry
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Proanthocyanidins / isolation & purification
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Quercetin / analogs & derivatives
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Quercetin / chemistry
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Quercetin / isolation & purification
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Rutin / analysis
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Secondary Metabolism
Substances
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Anthraquinones
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Mannosides
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Naphthalenes
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Plant Extracts
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Proanthocyanidins
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cassgranon D
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isoquercitrin
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quercitrin
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Rutin
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afzelin
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Quercetin
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aloe emodin
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Methanol