A new norsesquiterpene from the roots of Polyalthia laui

Nat Prod Res. 2017 Jul;31(14):1687-1692. doi: 10.1080/14786419.2017.1295236. Epub 2017 Feb 28.

Abstract

One new norsesquiterpene polyalone A (1), and one new natural product 9-keto-cyclocolorenone (2), along with three known analogues (3-5) were isolated from the roots of Polyalthia laui. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their cytotoxic activities and antibacterial activities.

Keywords: Polyalthia laui; antibacterial activities; cytotoxic activities; norsesquiterpene; polyalone A.

MeSH terms

  • Anti-Bacterial Agents / analysis
  • Anti-Bacterial Agents / pharmacology
  • Cytotoxins / analysis
  • Cytotoxins / isolation & purification
  • Humans
  • Molecular Structure
  • Plant Roots / chemistry
  • Polyalthia / chemistry*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology

Substances

  • Anti-Bacterial Agents
  • Cytotoxins
  • Sesquiterpenes
  • cyclocolorenone