Breast carcinoma associated with prolactinoma: A case report

Cancer Biol Ther. 2017 Mar 4;18(3):132-136. doi: 10.1080/15384047.2017.1294284. Epub 2017 Feb 17.

Abstract

We report a 28-year-old woman who presented with a 6-year history of milk-like discharge from both of her nipples and was diagnosed with prolactinoma based on computed tomography (CT) findings and serum prolactin level. Further breast examination revealed a mass located in the upper outer region of the left breast. She underwent subtotal pituitary tumor resection. Thereafter, modified radical mastectomy was performed for left breast cancer. Twelve years after treatment, prolactinoma recurrence was detected, and bromocriptine therapy was administered. No recurrence of breast cancer was discovered. Based on this case report, we stress the importance of prolactin levels due to their possible biologic effects on breast cancer induction or growth.

Keywords: Breast cancer; bromocriptine; prolactin; prolactinoma.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Breast Neoplasms / blood
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery
  • Female
  • Humans
  • Prolactinoma / blood
  • Prolactinoma / diagnosis*
  • Prolactinoma / pathology
  • Prolactinoma / surgery