The first total synthesis of anemarchalconyn and anemarcoumarin A

Abstract

Anemarchalconyn (1) and anemarcoumarin A (2), the natural bioactive compounds isolated from the rhizomes of Anemarrhena asphodeloides Bunge (Liliaceae), were first totally synthesized using easily available materials in short, convenient routes with overall yields of 32 and 48%.

Keywords: Anemarrhena asphodeloides; anemarchalconyn; anemarcoumarin A; total synthesis.