Synthesis of carbazoles based on gold-copper tandem catalysis

Chem Commun (Camb). 2017 Mar 25;53(24):3481-3484. doi: 10.1039/c7cc00103g. Epub 2017 Mar 9.

Abstract

An efficient synthetic method for carbazoles has been developed employing diazo anilinoalkynes as substrates. Sequential activation of the orthogonal functional groups embedded in diazo anilinoalkyne substrates by tandem gold-copper catalysis leads to the formation of highly substituted carbazoles. Substrate scope reveals a broad tolerability toward the substitution on aryl groups.