Quantitative estimation of electro-osmosis force on charged particles inside a borosilicate resistive-pulse sensor

Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug:2016:4228-4231. doi: 10.1109/EMBC.2016.7591660.

Abstract

Nano and micron-scale pore sensors have been widely used for biomolecular sensing application due to its sensitive, label-free and potentially cost-effective criteria. Electrophoretic and electroosmosis are major forces which play significant roles on the sensor's performance. In this work, we have developed a mathematical model based on experimental and simulation results of negatively charged particles passing through a 2μm diameter solid-state borosilicate pore under a constant applied electric field. The mathematical model has estimated the ratio of electroosmosis force to electrophoretic force on particles to be 77.5%.

MeSH terms

  • Boron / chemistry
  • Electrochemical Techniques
  • Electrodes
  • Models, Theoretical*
  • Nanopores*
  • Osmosis
  • Silicates / chemistry*

Substances

  • Silicates
  • Boron