A method to project clinical outcome topographies onto preoperative MRI to guide direct DBS targeting

Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug:2016:3993-3996. doi: 10.1109/EMBC.2016.7591602.

Abstract

The use of intraoperative MR and direct DBS targeting, relies on anatomical rather than functional data. Historical clinical outcome databases that have recorded stimulation location and magnitude of effect, can provide a useful adjunct in DBS targeting strategies. We present a method for generating clinical outcome topographies, and merging regions of effect onto a pre-operative MR, for surgical planning. The clinical outcome topographies are consistent with more intuitive strategies used by neurosurgeons. This method provides theoretical guidance during DBS target planning.

MeSH terms

  • Deep Brain Stimulation / methods*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Parkinson Disease / surgery*
  • Preoperative Care*
  • Subthalamic Nucleus / physiopathology
  • Treatment Outcome