Retraction

Abstract

Retraction: "Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A₂ and its transcription factor, activator protein-2" by Rao JS, Ertley RN, Rapoport SI, Bazinet RP, Lee HJ. The above article from Journal of Neurochemistry, published online on 13 April 2007 in Wiley Online Library (wileyonlinelibrary.com) and in volume 102, issue 6, pp. 1918-1927, has been retracted by agreement between the corresponding author Stanley Rapoport, co-author Richard Bazinet, the Journal's Editor-in-Chief Jörg Schulz, and John Wiley & Sons Ltd. The Editorial Office was contacted by the author Stanley Rapoport with the request to retract this and a related publication (see below), informing the Editor-in-Chief that the National Institutes of Health (NIH) had found Dr. Jagadeesh S. Rao guilty of research misconduct by falsifying data in the referenced paper. The Editorial Office was forwarded a letter signed by investigation committee members on behalf of NIH and NIA, which states: "[…] The National Institutes of Health (NIH) investigated allegations of research misconduct involving the falsification of data in "Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A₂ and its transcription factor, activator protein-2." Jagadeesh S. Rao, Renee N. Ertley, Stanley I. Rapoport, Richard P. Bazinet, and Ho-Joo Lee. J. Neurochemistry 102, 1918-1927, 2007. Based on the unanimous decision of a five member committee, composed of NIH investigators, NIH found that Dr. Jagadeesh Rao, corresponding author, knowingly and intentionally committed research misconduct by falsifying data in Figures 3 and 5 in the manuscript listed above. Dr. Rao was solely responsible for the falsification and all other authors were uninvolved. The report was submitted to the HHS Office of Research Integrity for its review. Because Dr. Rao was the corresponding author, Dr. Stanley I. Rapoport, Senior Advisor for the former Laboratory of Brain Physiology and Metabolism Section, is acting for Dr. Rao, who was his representative, and approves this request to retract this publication using the recommended language, in italics above." A related paper has also been retracted: Keleshian VL, Modi HR, Rapoport SI, Rao JS. (2013) Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex. J. Neurochem. 125: 63-73. References Keleshian V. L., Modi H. R., Rapoport S. I. and Rao J. S. (2013) Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex. J. Neurochem. 125, 63-73. Rao J. S., Ertley R. N., Rapoport S. I., Bazinet R. P. and Lee H. J. (2007) Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A₂ and its transcription factor, activator protein-2. J. Neurochem. 102, 1918-1927.