Renal function assessment in heart failure

J I Pérez Calvo; C Josa Laorden; I Giménez López

doi:10.1016/j.rce.2017.01.006

Renal function assessment in heart failure

Rev Clin Esp (Barc). 2017 Jun-Jul;217(5):267-288. doi: 10.1016/j.rce.2017.01.006. Epub 2017 Mar 1.

[Article in English, Spanish]

Authors

J I Pérez Calvo¹, C Josa Laorden², I Giménez López³

Affiliations

¹ Servicio de Medicina Interna, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, España; Facultad de Medicina, Universidad de Zaragoza, Zaragoza, España. Electronic address: jiperez@unizar.es.
² Servicio de Medicina Interna, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, España; Facultad de Medicina, Universidad de Zaragoza, Zaragoza, España.
³ Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, España; Facultad de Medicina, Universidad de Zaragoza, Zaragoza, España.

PMID: 28258719
DOI: 10.1016/j.rce.2017.01.006

Abstract

Renal function is one of the most consistent prognostic determinants in heart failure. The prognostic information it provides is independent of the ejection fraction and functional status. This article reviews the various renal function assessment measures, with special emphasis on the fact that the patient's clinical situation and response to the heart failure treatment should be considered for the correct interpretation of the results. Finally, we review the literature on the performance of tubular damage biomarkers.

Keywords: Biomarcadores; Biomarkers; Cistatina; Creatinina; Creatinine; Cystatin; Heart failure; Insuficiencia cardiaca; Insuficiencia renal; Renal failure; Urea.