Nuclear Decay Factors Crack Up mRNA

Agnieszka Tudek; Manfred Schmid; Torben Heick Jensen

doi:10.1016/j.molcel.2017.02.014

Nuclear Decay Factors Crack Up mRNA

Mol Cell. 2017 Mar 2;65(5):775-776. doi: 10.1016/j.molcel.2017.02.014.

Authors

Agnieszka Tudek¹, Manfred Schmid¹, Torben Heick Jensen²

Affiliations

¹ Department of Molecular Biology and Genetics, Aarhus University, C.F. Møllers Alle 3, Building 1130, 8000 Aarhus C., Denmark.
² Department of Molecular Biology and Genetics, Aarhus University, C.F. Møllers Alle 3, Building 1130, 8000 Aarhus C., Denmark. Electronic address: thj@mbg.au.dk.

PMID: 28257696
DOI: 10.1016/j.molcel.2017.02.014

Abstract

In this issue of Molecular Cell, Bresson et al. (2017) show that the nuclear RNA decay factors Nab3 and Mtr4 reshape the coding transcriptome during glucose starvation in budding yeast, placing nuclear mRNA metabolism as an important contributor of gene expression regulation.

MeSH terms

Nuclear Proteins / genetics
RNA Stability
RNA, Messenger*
RNA-Binding Proteins / genetics
Radioactivity
Saccharomyces cerevisiae / genetics
Saccharomyces cerevisiae Proteins / genetics*

Substances

Nuclear Proteins
RNA, Messenger
RNA-Binding Proteins
Saccharomyces cerevisiae Proteins