Bilateral primary pigmented nodular adrenal disease as a component of Carney syndrome - case report

Endokrynol Pol. 2017;68(1):70-72. doi: 10.5603/EP.2017.0008.

Abstract

We report a case of a 20-year-old patient with Cushing's syndrome as a component of Carney syndrome. Carney syndrome is an autosomal dominant disease with co-existing bilateral pigmented nodular adrenal disease, heart and skin myxoma, skin pigmentation, breast fibroadenoma, testicular and ovarian tumours, thyroid tumours, and pituitary adenomas. (Endokrynol Pol 2017; 68 (1): 70-72).

Keywords: Carney syndrome; Cushing's syndrome; adrenalectomy; primary pigmented nodular adrenal disease.

Publication types

  • Case Reports

MeSH terms

  • Adrenalectomy
  • Carney Complex / complications*
  • Cushing Syndrome / diagnosis
  • Cushing Syndrome / etiology*
  • Cushing Syndrome / metabolism
  • Cushing Syndrome / surgery
  • Cyclic AMP-Dependent Protein Kinase RIalpha Subunit / genetics
  • Female
  • Humans
  • Mutation, Missense
  • Young Adult

Substances

  • Cyclic AMP-Dependent Protein Kinase RIalpha Subunit
  • PRKAR1A protein, human