Hydrogel-Based Materials for Delivery of Herbal Medicines

ACS Appl Mater Interfaces. 2017 Apr 5;9(13):11309-11320. doi: 10.1021/acsami.6b16120. Epub 2017 Mar 23.

Abstract

Herbal medicine, as an integral component of oriental medicine, has assimilated into the lives of Asian people for millennia. The therapeutic efficiency of herbal extracts and ingredients has, however, been limited by various factors, including the lack of targeting capacity and poor bioavailability. Hydrogels are hydrophilic polymer networks that can imbibe a substantial amount of fluids. They are biocompatible, and may enable sustained drug release. Hydrogels, therefore, have attracted widespread studies in pharmaceutical formulation. This article first reviews the latest progress in the development of hydrogel-based materials as carriers of herbal medicines, followed by a discussion of the relationships between hydrogel properties and carrier performance. Finally, the promising potential of using hydrogels to combine medicinal herbs with synthetic drugs in one single treatment will be highlighted as an avenue for future research.

Keywords: drug delivery; herb; hydrogels; oriental medicine; sustained release.

MeSH terms

  • Biological Availability
  • Drug Delivery Systems
  • Herbal Medicine*
  • Hydrogels
  • Polymers

Substances

  • Hydrogels
  • Polymers