Abstract
Fluazaindolizine is a new highly effective and selective product for the control of plant parasitic nematodes. Specificity for nematodes coupled with absence of activity against the target sites of commercial nematicides suggests that fluazaindolizine has a novel mode of action. The discovery, structure-activity development and biological properties for this new class of nematicides are presented.
Keywords:
Fluazaindolizine; Nematicide; Plant parasitic nematodes; Structure-activity relationships.
Copyright © 2017 Elsevier Ltd. All rights reserved.
MeSH terms
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Animals
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Caenorhabditis elegans / drug effects
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Crops, Agricultural / parasitology
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Drosophila melanogaster / drug effects
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Heterocyclic Compounds, 2-Ring / chemical synthesis
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Heterocyclic Compounds, 2-Ring / pharmacology*
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Heterocyclic Compounds, 2-Ring / toxicity
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Indolizines / chemical synthesis
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Indolizines / pharmacology*
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Indolizines / toxicity
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Pesticides / chemical synthesis
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Pesticides / pharmacology*
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Pesticides / toxicity
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Plant Roots / parasitology
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Structure-Activity Relationship
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Sulfonamides / chemical synthesis
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Sulfonamides / pharmacology*
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Sulfonamides / toxicity
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Tylenchoidea / drug effects
Substances
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Heterocyclic Compounds, 2-Ring
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Indolizines
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Pesticides
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Sulfonamides
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fluazaindolizine