Magnetic Characterization of Iron Oxide Nanoparticles for Biomedical Applications

Methods Mol Biol. 2017:1570:47-71. doi: 10.1007/978-1-4939-6840-4_4.

Abstract

Iron oxide nanoparticles are of interest in a wide range of biomedical applications due to their response to applied magnetic fields and their unique magnetic properties. Magnetization measurements in constant and time-varying magnetic field are often carried out to quantify key properties of iron oxide nanoparticles. This chapter describes the importance of thorough magnetic characterization of iron oxide nanoparticles intended for use in biomedical applications. A basic introduction to relevant magnetic properties of iron oxide nanoparticles is given, followed by protocols and conditions used for measurement of magnetic properties, along with examples of data obtained from each measurement, and methods of data analysis.

Keywords: Anisotropy constant; Blocking temperature; Coercivity; Magnetic nanoparticles; Magnetic relaxation; Remanent magnetization; Saturation magnetization.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Ferric Compounds* / chemistry
  • Hydrophobic and Hydrophilic Interactions
  • Magnetic Fields
  • Magnetics* / methods
  • Magnetite Nanoparticles* / chemistry
  • Models, Theoretical
  • Temperature

Substances

  • Ferric Compounds
  • Magnetite Nanoparticles
  • ferric oxide