Ascending Spinal Cord Infarction Secondary to Recurrent Spinal Cord Cavernous Malformation Hemorrhage

J Stroke Cerebrovasc Dis. 2017 Apr;26(4):e72-e73. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.013. Epub 2017 Feb 22.

Abstract

We report a case of a 58-year-old Hispanic man who developed ascending paraparesis over several weeks secondary to recurrent hemorrhages and resulting in spinal cord ischemia from a low thoracic spinal cord cavernous malformation. The patient's deterioration was attributed to recurrent hemorrhage of a thoracic intramedullary cavernous malformation at T11 resulting in vascular congestion and spinal cord ischemia. The patient was found to have a heterozygous mutation on exon 13 of gene KRIT1, which was consistent with autosomal dominant familial cerebral cavernous malformations. Expedited surgical intervention potentially could have prevented this patient's progressive paraplegia.

Keywords: Spinal cord hemorrhage; T-2 weighted magnetic resonance imaging; cerebral cavernous malformation; spinal cord ischemia.

Publication types

  • Case Reports

MeSH terms

  • Afferent Pathways / diagnostic imaging
  • Afferent Pathways / pathology*
  • Hemangioma, Cavernous, Central Nervous System / complications*
  • Hemangioma, Cavernous, Central Nervous System / diagnostic imaging
  • Humans
  • Infarction / complications*
  • Infarction / diagnostic imaging
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Spinal Cord / diagnostic imaging
  • Spinal Cord / pathology*

Supplementary concepts

  • Familial cerebral cavernous malformation