Low vitamin D status and obesity: Role of nutritionist

Rev Endocr Metab Disord. 2017 Jun;18(2):215-225. doi: 10.1007/s11154-017-9410-7.

Abstract

Low vitamin D status and obesity have concomitantly reached epidemic levels worldwide. Up to now the direction of the association between low vitamin D status and obesity, the exact mechanisms responsible for this association and the clinical usefulness to increase vitamin D status for reducing adiposity still warrant further evaluation. The aim of the present review was to examine the current evidence linking low vitamin D status and obesity in relation to the role of the nutritionist. On the one side, considering obesity as a causal factor, low sun exposure in obese individuals due to their sedentary lifestyle and less outdoor activity, vitamin D sequestration in adipose tissue, and volumetric dilution of ingested or cutaneously synthesized vitamin D3 in the large fat mass of obese patients, might represent some of the factors playing a major role in the pathogenesis of the low vitamin D status. On the other side, the expression of both vitamin D3 receptors and enzymes responsible for vitamin D3 metabolism in adipocytes depicted a role for the low vitamin D status per se in the development of obesity by modulating adipocyte differentiation and lipid metabolism. Nutritionists need to accurately address the aspects influencing the low vitamin D status in obesity and the vitamin D supplementation in obese individuals.

Keywords: Diet; Environmental factor; Nutritionist; Obesity; Vitamin D.

Publication types

  • Review

MeSH terms

  • Adipocytes / drug effects
  • Adipocytes / metabolism
  • Adipose Tissue / drug effects
  • Adipose Tissue / metabolism
  • Adiposity / drug effects
  • Adiposity / physiology
  • Animals
  • Dietary Supplements
  • Humans
  • Lipid Metabolism / drug effects
  • Nutritionists*
  • Obesity / epidemiology
  • Obesity / etiology*
  • Physician's Role*
  • Vitamin D / administration & dosage
  • Vitamin D / blood
  • Vitamin D / physiology
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / complications*
  • Vitamin D Deficiency / diet therapy

Substances

  • Vitamin D